In the pharmaceutical industry, processing of various active pharmaceutical materials and one or more excipients is extensively involved. Most of these raw materials are fine powders, and these powders have different particle sizes, uneven density, poor fluidity, and easy delamination. These APIs must be processed in a granulation process to be used in tableting, capsule filling or other pharmaceutical processing. Dry granulators are particularly suitable for the granulation of drugs that are unstable under wet and hot conditions because of their various advantages.
The dry granulator is a kind of powder granulating equipment. Because the material itself contains a certain amount of crystallization water, it can directly form the uniform granule product required by the user without adding any binder. The particle density is large and there is no need for follow-up. Processing reduces the process, which not only reduces the cost of granulation, but also reduces dust pollution and improves the working environment of workers.
The dry granulator according to the principle of mechanical extrusion granulation process, the prepared dry powdery or fine crystal raw material with certain crystallization water is extruded into a thin sheet, and then processed by a granulation system through a sieve mesh. The size of the granular device is called a dry granulator.
The raw material of the dry granulator can be fed into the hopper or manually by vacuum feeder, and conveyed and compressed by the vertically placed feeding screw, pushed to the bite angle of the two squeeze rolls; the raw material is placed by the horizontally placed pressure roller Squeeze into thin sheets.
The pressure required for the material is transferred linearly to the pressure roller by means of a hydraulic device. The hydraulic device maintains a certain pre-pressure. The vertically aligned pressure roller ensures uniform material density. According to different particle size requirements, the mesh size of the screen in the granulator system of the dry granulator can be freely replaced.
Powder or fine crystal raw materials are directly made into granular products that meet the needs of users. No intermediates and additives are needed. After granulation, the product has uniform particle size, significantly increased bulk density, improved fluidity, and controls dust and powder. Waste. Easy to store and transport, control solubility, porosity and specific surface area. The dry granulator developed by the company can solve the difficult materials in the wet granulation process.
　　
Other medical tubes including a wide range of tubular medical products, such as endobronchial tube, tracheostomy tube, etc. An endobronchial tube is a kind of frequently-used medical tube related to a lung surgery, It is typically used in medical procedures such as bronchoscopy or during surgery to provide an Airway for the patient. Endobronchial tubes come in various sizes and left & right version to ensure proper ventilation. They are typically made of flexible materials such as PVC or silicone.
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