Production of veterinary clinical drug sensitivity test paper

Treatment of pigs and flock diseases in farms is very important, and drug susceptibility testing during treatment is critical. Due to the continuous emergence of new veterinary drug varieties, the drug-sensitive paper sheets produced on the market could not be purchased. This susceptibility testing has brought certain difficulties. In view of this situation, the author reviewed the relevant information, combined with the local reality, the use of veterinary drugs to explain the concentration, since the pharmaceutical sensitive paper, through dozens of clinical practice, the effect is good, are described below. The production and sterilization of paper sheets use good quality filter paper (quantitative filter paper), punched into a 6 mm diameter wafer with a punch, and placed into a vial for every l00 tablets, dry heat sterilization at 160°C. After 2 hours or autoclaving, dry at 60°C until use. Preparation of antibacterial drug concentration 1. Calculate the minimum concentration value according to the proportion of ingredients or drinking water on the drug use instructions converted into a basic unit dose (in order to accurately weigh the minimum drug value is appropriate, such as 0.5 grams, 1 gram, 2 grams Etc.), and how much material or water is required to be dispensed, is equivalent to the milliliters of distilled water added to the concentration of the drug used to make the soaked tablets. For example, the drug use instructions indicate that 5 grams of this product can be mixed with 50 kilograms of feed. The conversion method is 1 gram of this product can be mixed with 10 kilograms of feed, that is, 1 gram of this product is mixed with l0000 grams of feed, equivalent to a drug concentration of 1 g Add 10000 ml of distilled water to the product. 2. Concentration Preparation Accurately weigh the above basic unit dose (tablets should be ground into a powder and then weigh). Under aseptic conditions, dilute with distilled water according to the following items. According to the above conversion of l grams of this product plus 10000 ml of distilled water, that is, 1 g of this product plus 10l010l0 ml of distilled water. If there are l grams of the product mix 320 grams of feed, etc., can be changed to 1 gram of this product mix 320 grams of feed, that is, plus l048 ml of distilled water. This change is easy to form a separate item, does not affect the actual effect. Because when the ingredients can be divided according to the paper concentration of 1 g of this product mix 320 grams of feed for spices. If the amount of distilled water added is small or the distilled water on site is sufficient, it may not be diluted according to the above-mentioned multiple dilution method and may be directly diluted according to the proportion of the ingredients or the drinking water. Soaking and preservation of drug-responsive paper tablets Take 1 ml of the prepared drug solution into a sterilized vial containing 100 pieces of paper, soak it in the refrigerator for 1-2 hours, then take it out and dry it, and store it in a refrigerator. (save for 6 months).

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